CO Code

Appealing an Anthem (BCBS) CO-22 Denial

An Anthem (BCBS) CO-22 denial (coordination of benefits) is one of the most common claim rejections behavioral health therapists face. This guide explains exactly what caused the denial and the most effective appeal strategy for behavioral health practices.

What this denial means

The payer believes another insurer should pay first. This triggers when a patient has multiple insurance plans and the primary/secondary sequence was not established or was submitted out of order.

Your appeal strategy

Verify the patient's COB information and confirm which plan is primary. Submit the EOB from the primary payer with the secondary claim. If your payer is primary but coded the claim as secondary, provide the COB letter or member insurance card showing your payer's priority status.

What Anthem (BCBS) requires

Appeal Address
Anthem Blue Cross Appeals Unit
P.O. Box 60007
Los Angeles, CA 90060
Response Window

30 calendar days (Level-1 appeal)

External Review Deadline

60 days from Level-1 denial

Fax

1-866-755-2680

Provider Portal
File online
Anthem (BCBS) Parity Notes

Anthem (now Elevance Health) is a major BCBS licensee operating in ~14 states. File appeals to the state-specific Anthem entity; addresses vary by state. Behavioral health managed through Sydney Health / Anthem Behavioral Health.

Generate your Anthem (BCBS) CO-22 appeal letter

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Frequently asked questions

How long does Anthem (BCBS) have to respond to a CO-22 appeal?

Under federal regulations and most state prompt-payment laws, Anthem (BCBS) must respond to a Level-1 internal appeal within 30 calendar days. If you receive an adverse determination, you typically have 60 calendar days from the date of the Level-1 denial to request external review. Send the appeal via certified mail or through the payer's portal and keep documentation of the submission date.

Does MHPAEA apply to CO-22 denials?

CO-22 denials are not directly tied to mental health parity protections in most cases — this code is a general adjudication rule that applies equally to all claim types. MHPAEA may still be relevant if the underlying reason for the denial differs for mental health vs. medical/surgical services. When in doubt, include a parity argument in your appeal.

Can I appeal a CO-22 denial more than once?

Yes. Most payers, including Anthem (BCBS), allow at least two levels of internal appeal (Level-1 and Level-2 or "expedited" review). After exhausting internal appeals, you have the right to request an Independent Medical Review (IMR) or external review through your state insurance commissioner. Keep copies of every appeal, submission confirmation, and payer response.

What documentation do I need to appeal a CO-22 denial from Anthem (BCBS)?

At minimum: the original Explanation of Benefits (EOB) or Remittance Advice (RA) showing the CO-22 denial, the original claim details (CPT code, date of service, NPI, charge amount), and any clinical documentation supporting medical necessity. Submit everything in one packet with a cover letter citing the specific denial code, the date of service, and the claim number.

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